]> C16.0 Cardia, esophagogastric junction (EGJ) C16.1 Fundus of stomach, proximal 5 centimeters (cm) only C16.2 Body of stomach, proximal 5 cm only Note 2: Effective with AJCC TNM 7th Edition, there are separate stage groupings for squamous cell carcinoma and adenocarcinoma of the esophagus. Since squamous cell carcinoma typically has a poorer prognosis than adenocarcinoma, a tumor of mixed histopathologic type or a type that is not otherwise specified should be classified as squamous cell carcinoma. Note 3: Effective with AJCC TNM 7th Edition, histologic grade is required for stage grouping. &commontumorsizestomach; CS Extension Note 1: For this site, AJCC defines Tis as high-grade dysplasia, which includes "all non-invasive neoplastic epithelium that was previously called carcinoma in situ." Cancers stated to be noninvasive or in situ are classified as Tis. High-grade dysplasia is generally not reportable in cancer registries, but if a registry does collect it, code 000 should be used. Note 2: Use codes 110, 120, and 160 in preference to code 150 if information about the depth of invasion into the layers of the polyp is available. Note 3: Ignore intraluminal extension to adjacent segment(s) of esophagus or to more distal parts of stomach and code depth of invasion or extra-gastric spread as indicated. Note 4: If the diagnosis states linitis plastica and no other information regarding extension is available, use code 350. Linitis plastica is defined as diffuse involvement of the entire stomach wall. Note 5: Codes 600-700 are used for contiguous extension from the site of origin. Discontinuous involvement is coded in CS Mets at DX, except for implants within the stomach (code 300). Code Description TNM 7 Map TNM 6 Map SS77 Map SS2000 Map 000 In situ, intraepithelial, non-invasive; high-grade dysplasia Tis Tis IS IS 050 (Adeno)carcinoma, noninvasive, in a polyp Tis Tis IS IS 100 Invasive tumor confined to mucosa, NOS, (including intramucosal, NOS) T1a T1 L L 110 Invades lamina propria T1a T1 L L 120 Invades muscularis mucosae T1a T1 L L 125 Stated as T1a with no other information on extension T1a T1 L L 130 ERROR T1 L L 140 ERROR T1 L L 150 Tumor in polyp NOS T1NOS T1 L L 160 T1b T1 L L 170 Stated as T1 [NOS] with no other information on extension T1NOS T1 L L 200 Invades into but not through muscularis propria T2 T2a L L 300 T1NOS T1 L L 350 T2 T2a RE L 360 Stated as T2 with no other information on extension T2 T2NOS L L 400 T3 T2b L L 420 T3 T3 RE RE 430 OBSOLETE DATA CONVERTED V0203 See code 480 Stated as T3 [NOS] ERROR ERROR ERROR ERROR 450 T3 T2b RE RE 480 Stated as T3 with no other information on extension T3 T2b L RE 500 Invasion of/through serosa (mesothelium) (tunica serosa) (visceral peritoneum), including perforation of visceral peritoneum covering the gastric ligaments or the omentum WITHOUT invasion of adjacent structures T4a T3 RE RE 550 500 + 450 T4a T3 RE RE 570 T4a T4 RE RE 580 Stated as T4a with no other information on extension T4a T4 RE RE 600 T4a T4 RE RE 605 T4b T4 RE RE 610 T4a T4 RE RE 615 605 + 570 T4b T4 RE RE 700 T4a T4 D D 710 ERROR ERROR ERROR ERROR 720 ERROR ERROR ERROR ERROR 800 T4b T4 D D 805 Stated as T4b with no other information on extension T4b T4 D D 810 Stated as T4 [NOS] with no other information on extension T4NOS T4 RE RE 820 ERROR ERROR ERROR ERROR 950 No evidence of primary tumor T0 T0 U U 999 TX TX U U &generalcstsexteval; CS Lymph Nodes Note 1: Code only regional nodes and nodes, NOS, in this field. Distant nodes are coded in the field Mets at DX. Note 2: If information about named regional lymph nodes is available, use codes 100, 400, 450 or 500, rather than codes 610, 660, or 710. Code Description TNM 7 Map TNM 6 Map SS77 Map SS2000 Map 000 No regional lymph node involvement N0 N0 NONE NONE 100 ^ * RN RN 400 ^ * D RN 420 ERROR * D D 450 ^ * D D 500 Regional lymph node(s), NOS ^ * RN RN 600 N1 N1 RN RN 610 Stated as pathologic N1 with no other information on regional lymph nodes N1 N1 RN RN 650 N2 N2 RN RN 660 Stated as pathologic N2 with no other information on regional lymph nodes N2 N1 RN RN 700 N3 N3 RN RN 710 Stated as pathologic N3 with no other information on regional lymph nodes N3 N2 RN RN 800 Lymph nodes, NOS N1 N1 RN RN 999 NX NX U U ^ For CS Lymph Nodes codes 100-400, 450, and 500 ONLY, when CS Lymph Nodes Eval is 0, 1, 5, or 9, the N category is assigned from the Lymph Nodes Clinical Evaluation AJCC 7 Table, using Regional Nodes Positive and CS Site-Specific Factor 1; when CS Lymph Nodes Eval is 2, 3, 6, 8, or not coded, the N category is determined from the Lymph Nodes Pathologic Evaluation AJCC 7 Table Also Used When CS Lymph Nodes Eval Is Not Coded, using Regional Nodes Positive. * For CS Lymph Nodes codes 100-500 ONLY, when CS Lymph Nodes Eval is 0, 1, 5, or 9, the N category is assigned from the Lymph Nodes Clinical Evaluation AJCC 6 Table, using Regional Nodes Positive and CS Site-Specific Factor 1; when CS Lymph Nodes Eval is 2, 3, 6, 8, or not coded, the N category is determined from the Lymph Nodes Pathologic Evaluation AJCC 6 Table Also Used When CS Lymph Nodes Eval Is Not Coded, using Regional Nodes Positive. &generalregnodeseval; &commonreglnpos_active; &generalreglnexam; CS Mets at DX Code Description TNM 7 Map TNM 6 Map SS77 Map SS2000 Map 00 No distant metastasis M0 M0 NONE NONE 10 M1 M1 D D 40 M1 M1 D D 50 M1 M1 D D 60 M1 M1 D D 99 M0 MX U U &generalmetseval; CS Site-Specific Factor 1 Clinical Assessment of Regional Lymph Nodes Note 1: In the rare instance that the number of clinically positive nodes is stated but a clinical N category is not stated, code 1-2 nodes as 100 (Clinically N1), 3-6 nodes as 200 (Clinically N2), and 7 or more nodes as 300 (Clinically N3). Note 2: If there is no diagnostic work-up to assess regional lymph nodes, use code 999. Do not apply the inaccessible nodes rule that presumes unmentioned nodes to be negative. Note 3: For legacy data coded in the Stomach schema in CS Version 1, N1 was assigned for 1-6 nodes positive, N2 for 7-15 nodes positive, and N3 for 16 and more nodes positive. Note 4: For data coded in the EsophagusGEJunction schema in CS Version 2, when number of nodes involved is unknown, N1 and N2 are mapped to N1 for AJCC 6 staging, and N3 is mapped to N2 for AJCC 6 staging. Code Description 000 Nodes not clinically evident; imaging of regional nodes performed and nodes not mentioned 100 200 300 400 Clinically positive regional nodes, NOS 888 988 999 ¬appssfactor2; &commonssf3esophagus; &commonssf4esophagus; &commonssf5esophagus; ¬appssfactor6; ¬appnewssf7; ¬appnewssf8; ¬appnewssf9; ¬appnewssf10; ¬appnewssf11; ¬appnewssf12; ¬appnewssf13; ¬appnewssf14; ¬appnewssf15; ¬appnewssf16; ¬appnewssf17; ¬appnewssf18; ¬appnewssf19; ¬appnewssf20; ¬appnewssf21; ¬appnewssf22; ¬appnewssf23; ¬appnewssf24; &commonssf25stomach; &commonhistinclusioncarcinomanongistnet; &commonhistologyexclusions1; &commonstageesophagus_notapptnm7; AJCC TNM 6 Stage T N M Stage T0 N0 M0 ERROR T0 N1 M0 IB T0 N2 M0 II T0 N3 M0 IV T0 NX M0 UNK T0 N0 M1 IV T0 N1 M1 IV T0 N2 M1 IV T0 N3 M1 IV T0 NX M1 IV T0 N0 MX UNK T0 N1 MX UNK T0 N2 MX UNK T0 N3 MX IV T0 NX MX UNK Tis N0 M0 0 Tis N1 M0 ERROR Tis N2 M0 ERROR Tis N3 M0 ERROR Tis NX M0 0 Tis N0 M1 ERROR Tis N1 M1 ERROR Tis N2 M1 ERROR Tis N3 M1 ERROR Tis NX M1 ERROR Tis N0 MX 0 Tis N1 MX ERROR Tis N2 MX ERROR Tis N3 MX ERROR Tis NX MX 0 T1 N0 M0 IA T1 N1 M0 IB T1 N2 M0 II T1 N3 M0 IV T1 NX M0 UNK T1 N0 M1 IV T1 N1 M1 IV T1 N2 M1 IV T1 N3 M1 IV T1 NX M1 IV T1 N0 MX UNK T1 N1 MX UNK T1 N2 MX UNK T1 N3 MX IV T1 NX MX UNK T2NOS N0 M0 IB T2NOS N1 M0 II T2NOS N2 M0 IIIA T2NOS N3 M0 IV T2NOS NX M0 UNK T2NOS N0 M1 IV T2NOS N1 M1 IV T2NOS N2 M1 IV T2NOS N3 M1 IV T2NOS NX M1 IV T2NOS N0 MX UNK T2NOS N1 MX UNK T2NOS N2 MX UNK T2NOS N3 MX IV T2NOS NX MX UNK T2a N0 M0 IB T2a N1 M0 II T2a N2 M0 IIIA T2a N3 M0 IV T2a NX M0 UNK T2a N0 M1 IV T2a N1 M1 IV T2a N2 M1 IV T2a N3 M1 IV T2a NX M1 IV T2a N0 MX UNK T2a N1 MX UNK T2a N2 MX UNK T2a N3 MX IV T2a NX MX UNK T2b N0 M0 IB T2b N1 M0 II T2b N2 M0 IIIA T2b N3 M0 IV T2b NX M0 UNK T2b N0 M1 IV T2b N1 M1 IV T2b N2 M1 IV T2b N3 M1 IV T2b NX M1 IV T2b N0 MX UNK T2b N1 MX UNK T2b N2 MX UNK T2b N3 MX IV T2b NX MX UNK T3 N0 M0 II T3 N1 M0 IIIA T3 N2 M0 IIIB T3 N3 M0 IV T3 NX M0 UNK T3 N0 M1 IV T3 N1 M1 IV T3 N2 M1 IV T3 N3 M1 IV T3 NX M1 IV T3 N0 MX UNK T3 N1 MX UNK T3 N2 MX UNK T3 N3 MX IV T3 NX MX UNK T4 N0 M0 IIIA T4 N1 M0 IV T4 N2 M0 IV T4 N3 M0 IV T4 NX M0 UNK T4 N0 M1 IV T4 N1 M1 IV T4 N2 M1 IV T4 N3 M1 IV T4 NX M1 IV T4 N0 MX IV T4 N1 MX IV T4 N2 MX IV T4 N3 MX IV T4 NX MX UNK TX N0 M0 UNK TX N1 M0 UNK TX N2 M0 UNK TX N3 M0 IV TX NX M0 UNK TX N0 M1 IV TX N1 M1 IV TX N2 M1 IV TX N3 M1 IV TX NX M1 IV TX N0 MX UNK TX N1 MX UNK TX N2 MX UNK TX N3 MX IV TX NX MX UNK &commonsummarystage; &commonstageesophagusgejunction_squamoustnm7; &commonstageesophagusgejunction_adenocarcinomatnm7; Lymph Nodes Clinical Evaluation 7th Table Note: This table is used when CS Lymph Nodes is 100-400, 450, and 500 ONLYand CS Lymph Nodes Eval is 0, 1, 5, or 9. The N category is determined based on the number of positive regional nodes in Regional Nodes Positive and the value of CS Site-Specific Factor 1, Clinical Assessment of Regional Lymph Nodes. Regional Nodes Positive SSF1 000 0 SSF1 100 100 SSF1 200 200 SSF1 300 300 SSF1 400 400 SSF1 888 888 SSF1 988 988 SSF1 999 999 00 N1 N1 N2 N3 N1 ERROR ERROR N1 01-02 N1 N1 N2 N3 N1 ERROR ERROR N1 03-06 N2 N2 N2 N3 N2 ERROR ERROR N2 07-90 N3 N3 N3 N3 N3 ERROR ERROR N3 95-97 N1 N1 N2 N3 N1 ERROR ERROR N1 98-99 N1 N1 N2 N3 N1 ERROR ERROR N1 Lymph Nodes Pathologic Evaluation 7th Table Also Used When CS Reg Nodes Eval is Not Coded Note: This table is used when CS Lymph Nodes is 100-400, 450, and 500 ONLY and CS Lymph Nodes Eval is 2, 3, 6, 8, or not coded. The N category is determined based on the number of positive regional nodes in Regional Nodes Positive. Regional Nodes Positive N Category 00-02 N1 03-06 N2 07-90 N3 95-99 N1 &commonextralymphnodesclinicalevalstomach; &commonextralymphnodespathologicevalstomach; Histologies Stage Table Note 1: The determination of AJCC stage group from T, N, M, and grade for EsophagusGEJunction depends further on histologic type. Since squamous cell carcinoma typically has a poorer prognosis than adenocarcinoma, a tumor of mixed histopathologic type (including a squamous component or NOS histology) or a type that is not otherwise specified should be staged as squamous cell carcinoma. Note 2: This table shows the selection of the appropriate version of the AJCC Stage table based on histology. In the table below, Squamous maps to the table AJCC TNM 7 Stage Squamous, and Adenocarcinoma maps to the table AJCC TNM 7 Stage Adenocarcinoma. Histologic Type ICD-O-3 Stage Table 8000-8046 Squamous 8050 Adenocarcinoma 8051-8131 Squamous 8140-8147 Adenocarcinoma 8148-8152 Squamous 8154-8157 Squamous 8160-8162 Adenocarcinoma 8170-8175 Squamous 8180-8221 Adenocarcinoma 8230-8231 Squamous 8243-8245 Squamous 8247-8248 Squamous 8250-8507 Adenocarcinoma 8508-8513 Squamous 8514-8551 Adenocarcinoma 8560-8570 Squamous 8571-8574 Adenocarcinoma 8575 Squamous 8576 Adenocarcinoma 8940-8941 Adenocarcinoma 8950 Squamous 8980-8981 Squamous